Benefit of Pomegranate extract – What are some of the health benefits of Pomegranate juice or supplements?
January 2 2017

Benefit of Pomegranate extract
Pomegranate is a delicious fruit with many beneficial compounds. The benefit of pomegranate is that it has substances, such as polyphenols, that have antioxidant, anti-viral, and anti-tumor activity. Pomegranate may also be of benefit in maintaining healthy cholesterol and triglyceride levels. Additional research points to the benefit of pomegranate in osteoarthritis and prostate health.
Actual human studies with pomegranate juice or supplements are few. Therefore we still don’t know the full benefits and side effects of long term pomegranate use. Thus far all indications point to this fruit being an excellent addition to one’s diet. If you plan to take pomegranate extract supplements daily, we suggest taking it with other natural fruit extracts such as goji berry.

Herbal supplements with health benefits
Herbs that have interesting properties that you can buy include curcumin pill, goji berry, maqui berry, ginger, camu camu, graviola supplement.

Buy pomegranate, visit this article multivitamin. You will find the latest research on pomegranate extract or to sign up up to a FREE alternative health research newsletter

Pomegranate extract 500 mg, 60 Capsules
Pomegranate extract (Punica granatum) from a pure, whole-fruit source.  Get the benefits of pomegranate juice and avoid all the calories and sugar (fructose).

Pomegranate Supplement Facts
Pomegranate extract – 500 mg *
Recommendation: Take 1 or 2 pomegranate capsules daily with food or water.

* Pomegranate daily value not established.

How to eat a pomegranate
Pomegranate juice can be used to make gelatin desserts, sauces and dressing, while the seeds can be used as a garnish or eaten raw or added to salads.

Pomegranate seed
Inside the pomegranate fruit are hundreds of seeds packed in compartments that are separated by bitter, cream-colored membranes. Each tiny, edible seed is surrounded by a translucent, brilliant-red pulp that has a sparkling sweet-tart flavor.

The nearly round, 3 to 5 inch wide pomegranate fruit is crowned at the base by the prominent calyx. The tough, leathery pomegranate skin or rind is typically yellow overlaid with light or deep pink or rich red. The interior is separated by membranous walls and white, spongy, bitter tissue into compartments packed with sacs filled with sweetly acid, juicy, red, pink or whitish pulp or aril. In each sac there is one angular, soft or hard seed.

Availability of Pomegranate
The pomegranate fruit can be made into pomegranate juice, pomegranate extract, jam, jelly, pomegranate juice concentrate, molasses, syrup, tea, and even pomegranate wine and martini. Pomegranate pills are available and are a good option in order to avoid the calories.

Benefit of Pomegranate Juice
Even though pomegranate has substances, such as polyphenols, that have antioxidant, anti-viral, and anti-tumor activity, it will take many years to find out how the health benefit of pomegranate juice in humans and how many ounces are required. One drawback with any type of juice is the excess calories and fructose. Hence, a pomegranate extract supplement could be useful by reducing the caloric intake from the pomegranate juice. This is particularly appropriate for those who are overweight.

Benefit of pomegranate for breast cancer
Breast cancer chemopreventive properties of pomegranate (Punica granatum) fruit extracts in a mouse mammary organ culture.
Eur J Cancer Prev. 2004.
Mehta R, Lansky EP. University of Illinois at Chicago, Chicago
We previously reported anticancer effects of pomegranate extracts in human breast cancer cells in vitro and also chemopreventive activity of pomegranate fermented juice polyphenols (W) in a mouse mammary organ culture. In the present study we decided to expand the investigations to also include an evaluation of the potential chemopreventive efficacy of a purified chromatographic peak of W (Peak B), and also of whole pomegranate seed oil. The results highlight enhanced breast cancer preventive potential both for the purified compound peak B and for pomegranate seed oil, both greater than that previously reported for pomegranate fermented juice polyphenols.

Benefit of pomegranate for osteoarthritis, arthritis pain
Pomegranate fruit extracts can block enzymes that contribute to osteoarthritis according to a Case Western Reserve University School of Medicine study published in the September 2005 issue of the Journal of Nutrition. The study looked at the ability of an extract of pomegranate fruit against Interleukin-1b (IL-1b), a pro-inflammatory protein molecule that plays a key role in cartilage degradation in osteoarthritis. Plant-based flavonoids found in fruits, leaves and vegetables have attracted a lot of attention for their beneficial health effects in various diseases. Pomegranate, in particular, has been found to possess antioxidant and anti-inflammatory properties that have potential therapeutic benefits in a variety of diseases. The Case study demonstrated for the first time the ability of pomegranate fruit extracts to slow the deterioration of human cartilage.

Benefit of pomegranate for prostate health
Pomegranate extract may prevent prostate cancer or slow its growth, if results of lab experiments conducted at the University of Wisconsin in Madison translate to real-world benefits. Pomegranates are high in polyphenolic compounds, making its juice higher in antioxidant activity than red wine and green tea. When they incubated prostate cancer cells with low concentrations of pomegranate extract, they observed a dose-related inhibition of cell growth. In prostate cancer cells driven by male hormones (androgens) and expressing prostate specific antigen (PSA), treatment with pomegranate extract decreased androgen receptors and PSA expression. When human prostate cancer cells were injected into mice, feeding the animals pomegranate extract delayed the appearance of tumors. Tumor growth was significantly inhibited and survival was prolonged.

In men with recurrent prostate cancer, drinking 8 ounces per day of pomegranate juice significantly increases the time it takes for an increase in levels of prostate specific antigen (PSA), an indicator of prostate cancer. Before the men in the study began consuming pomegranate juice, the average PSA doubling time, a measure of tumor activity, was 15 months. The average time after treatment was 37 months. So, there was almost a 2-year increase in the doubling time. Pomegranate juice contains a number of antioxidants thought to have anti-cancer effects, Pomegranate juice contains estrogen-like plant substances called phytoestrogens that could be useful in combating prostate cancer. Pomegranate juice therapy was well tolerated and no serious adverse effects were reported. In addition to the beneficial increase in PSA doubling time, in vitro testing showed decreased cancer cell division and proliferation and increased cancer cell death. Urine testing confirmed the presence of pomegranate antioxidants in all men. The study was funded by the Stewart and Lynda Resnick Trust, which own the POM Wonderful pomegranate juice company.

Q. Is prostate growth shrinking a health benefit of pomegranate juice drinking?
A. We have not seen enough human studies to determine if a health benefit of pomegranate juice involves the effective treatment of prostate enlargement.

Benefit of pomegranate for cholesterol and blood lipids
Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia.
J Med Food. 2004.
This study assessed the effect of concentrated pomegranate juice consumption on lipid profiles of type II diabetic patients with hyperlipidemia. In this quasi-experimental study 22 otherwise healthy diabetic patients, 14 women and eight men were recruited from among patients referred to the Iranian Diabetes Society. The patients were followed for 8 weeks to establish a baseline for normal dietary intake before beginning the concentrated pomegranate juice intervention. During the pre-study period a 24-hour food recall and food records (recording flavonoid-rich foods) were completed every 10 days. At the end of the eighth week, anthropometric and biochemical assessments were done. Thereafter the patients consumed 40 g/day of concentrated pomegranate juice for 8 weeks, during which time dietary assessment was continued. After completing the study, anthropometric and blood indices were again evaluated. After consumption of concentrated pomegranate juice, significant reductions were seen in total cholesterol, low-density lipoprotein (LDL)-cholesterol, LDL-cholesterol / high-density lipoprotein (HDL)-cholesterol, and total cholesterol/HDL-cholesterol. But, there were no significant changes in serum triacylglycerol and HDL-cholesterol concentrations. Anthropometric indices, physical activity, kind and doses of oral hypoglycemic agents, and the intakes of nutrients and flavonoid-rich foods showed no change during the concentrated pomegranate juice consumption period. It is concluded that concentrated pomegranate juice consumption may modify heart disease risk factors in hyperlipidemic patients, and its inclusion therefore in their diets may be beneficial.

Benefit of pomegranate for stroke
Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation.
Clin Nutr. 2004.
Dietary supplementation with polyphenolic antioxidants to animals was shown to be associated with inhibition of LDL oxidation and macrophage foam cell formation, and attenuation of atherosclerosis development. We investigated the effects of pomegranate juice (PJ, which contains potent tannins and anthocyanins) consumption by atherosclerotic patients with carotid artery stenosis (CAS) on the progression of carotid lesions and changes in oxidative stress and blood pressure. Ten patients were supplemented with pomegranate juice for 1 year and five of them continued for up to 3 years. Blood samples were collected before treatment and during pomegranate juice consumption. In the control group that did not consume pomegranate juice, common carotid intima-media thickness (IMT) increased by 9% during 1 year, whereas, pomegranate juice consumption resulted in a significant IMT reduction, by up to 30%, after 1 year. The results of the present study thus suggest that pomegranate juice consumption by patients with carotid artery stenosis decreases carotid IMT and systolic blood pressure and these effects could be related to the potent antioxidant characteristics of pomegranate juice polyphenols.

Benefit of pomegranate in menopause
Pomegranate extract improves a depressive state and bone properties in menopausal syndrome model ovariectomized mice.
J Ethnopharmacol. 2004.
Pomegranate is known to contain estrogens (estradiol, estrone, and estriol) and show estrogenic activities in mice. In this study, we investigated whether pomegranate extract is effective on experimental menopausal syndrome in ovariectomized mice. Prolongation of the immobility time in forced swimming test, an index of depression, was measured 14 days after ovariectomy. The bone mineral density (BMD) of the tibia was measured by X-ray absorptiometry and the structure and metabolism of bone were also analyzed by bone histomorphometry. Administration of pomegranate extract (juice and seed extract) for 2 weeks to ovariectomized mice prevented the loss of uterus weight and shortened the immobility time compared with 5% glucose-dosed mice (control). In addition, ovariectomy-induced decrease of BMD was normalized by administration of the pomegranate extract. The bone volume and the trabecular number were significantly increased and the trabecular separation was decreased in the pomegranate-dosed group compared with the control group. Some histological bone formation/resorption parameters were significantly increased by ovariectomy but were normalized by administration of the pomegranate extract. These changes suggest that the pomegranate extract inhibits ovariectomy-stimulated bone turnover. It is thus conceivable that pomegranate is clinically effective on a depressive state and bone loss in menopausal syndrome in women.

Benefit of Pomegranate questions
Q. How does 500 mg of pomegranate extract compare to the benefit of pomegranate juice? I would like to substitute the pomegranate extract capsules for for the juice that I’ve been drinking.
A. This is a good question and we really don’t have a good answer. It is very difficult to compare since no studies have been done to find out which form is better and what the equivalency of pomegranate juice is to pomegranate extract. The pomegranate juice has a lot of calories and fructose. On average, most people take 1 to 3 pomegranate capsules a day. Studies in the future could perhaps shed some light.

Q. Can pomegranate help with weight loss?
A. We have not seen human research thus far regarding pomegranate supplements for weight loss. Herbs that could reduce appetite include green tea extract and hoodia. You can purchase Green Tea Extract and Hoodia Extract here.

Q. I use pomegranate peel as compost.

Q. My question is on pomegranate nutrition fact, specifically pomegranate calories. How many calories would be in a pomegranate about four inches in diameter?
A. If you eat a pomegranate fruit of that size, expect to have about 120 calories. Pomegranate health benefits and antioxidant benefit can be also obtained through a supplement if you don’t wish to ingest about 25 grams of sugar. One option is to alternate between drinking pomegranate juice, taking a pomegranate supplement, or eating a whole pomegranate fruit.

Q. I have learned how to make pomegranate juice and now I am interested in knowning: Is pomegranate antioxidant benefit as good as blueberry or cranberry?
A. It is difficult to say. We prefer using small amounts of a variety of beneficial herbs and extracts as opposed to high dosages of just one or two. Pomegranate has great antioxidant, but so do countless fruit extracts. The benefit of pomegranate fruit cannot be easily compared to goji, berries, noni, and many other plants. They all should be part of one’s diet.

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