Maca herb information and SSRI medication combination
Maca sexual help for those on SSRI anti-depressant drugs such as Prozac, Paxil, Celexa, and Zoloft
Maca Studies on sexual enhancement and energy
Maca Review
benefit for health and longevity
January 2 2017

Review and benefit
Maca is a root-like vegetable shaped like a radish. It grows in the harsh climate of the Andes Mountains in South America. Maca is traditionally used in the Andean region for its supposed aphrodisiac and fertility-enhancing properties. recently studies have shown that it can be of benefit in reversing the sexual disrupting effects of medications used for treating depression. Many people report that Passion Rx with Yohimbe also helps reverse the sexual dysfunction caused by prescription antidepressants.

The Food and Drug Administration (FDA) has approved these SSRI medications to treat depression:
Citalopram (Celexa)
Escitalopram (Lexapro)
Fluoxetine (Prozac)
Paroxetine (Paxil, Pexeva)
Sertraline (Zoloft)
Vilazodone (Viibryd)

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Maca Supplement Facts – Highest Quality
Maca Root – 500 mg
Suggested Use, dosage, how much to take: 1 or two maca capsules in the morning, or as recommended by your health care professional.

Maca for the management of SSRI-induced sexual dysfunction
A double-blind, randomized, pilot dose-finding study of maca root for the management of SSRI-induced sexual dysfunction.
CNS Neurosci Ther. 2008; Dording CM, Fisher L, Papakostas G, Farabaugh A, Sonawalla S, Mischoulon D. Depression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
We sought to determine whether maca, a Peruvian plant, is effective for selective-serotonin reuptake inhibitor (SSRI)-induced sexual dysfunction. We conducted a double-blind, randomized, parallel group dose-finding pilot study comparing a low-dose maca herb (1.5 grams /day) to a high-dose (3 g/day) maca regimen in 20 remitted depressed outpatients (mean age 36 years; 17 women) with SSRI-induced sexual dysfunction. Subjects on 3 grams /day maca had a significant improvement, but subjects on 1.5 grams /day maca did not. Maca was well tolerated. Maca root may alleviate SSRI-induced sexual dysfunction, and there may be a dose-related effect. Maca may also have a beneficial effect on libido.

Other plant aphrodisiacs
Cistanche plant for sexual enhancement can be taken along with maca root herb if the dosages are low

What Maca extract research says about its sexual potency benefits
In one study researchers fed high dosages of maca extracts to male mice. The frequency with which they coupled with female mice tripled.  In rats with erectile dysfunction the time needed between successive couplings was reduced by half.

Maca prevents prostate enlargement in mice
Antagonistic effect of Lepidium meyenii (red maca) on prostatic hyperplasia in adult mice.
Andrologia. 2008: Gonzales GF, Gasco M, Malheiros-Pereira A, Gonzales-Castañeda C. Gonzales GF, Gasco M, Malheiros-Pereira A, Gonzales-Castañeda C. Faculty of Sciences and Philosophy, Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru.
The present study was designed to determine the effect of red maca in the prostate hyperplasia induced with testosterone enanthate in adult mice. Our results show maca has an anti-hyperplastic effect on the prostate of adult mice when hyperplasia was induced with testosterone acting first at prostatic stromal level.

Maca Research studies
The in vitro biological activity of Lepidium meyenii maca extracts.
Cell Biol Toxicol. 2006.
Valentova K, Buckiova D, Kren V, Peknicova J, Ulrichova J, Simanek V.
Institute of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacky University, Olomouc.
The biological activity of methanolic and aqueous extracts from dehydrated hypocotyls of Lepidium meyenii (Brassicaceae, vernacular name maca ), was studied on rat hepatocytes and human breast cancer MCF-7 cells. The maca extracts did not exhibit cytotoxicity in hepatocyte primary cultures up to 10 mg/ml as measured by the MTT viability test, and lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) leakage. Moreover, after 72 h, extracts inhibited LDH and AST leakage from the hepatocytes. When hepatocytes were intoxicated by t-butyl hydroperoxide, neither extract prevented oxidative damage. Both maca extracts showed weak antioxidant activity for aqueous and methanolic extracts. Thus, the observed effect on spontaneous enzyme leakage is probably mediated through mechanisms other than antioxidant activity. Both methanolic and aqueous maca extracts have shown estrogenic activity comparable with that of silymarin in MCF-7 cell line. Maca estrogenicity was exhibited. The findings in the present study show that maca does not display in vitro liver toxicity. In contrast, a slight cell protection effect, probably not mediated by antioxidant capacity, was noted. Maca extracts exhibited estrogenic activity comparably to the effect of silymarin in MCF-7 cells.

Maca reversed the lead acetate induced-Damage on reproductive function in male rats.
Food Chem Toxicol. 2006; Rubio J, Riqueros MI, Gasco M, Yucra S, Miranda S, Gonzales GF.
Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru; Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru
Rats were treated with lead acetate (LA) (i.p.) for 35 days with or without Maca herb. Maca was co-administrated orally from day 18 to day 35. The lengths of stages of the seminiferous epithelium were assessed by transillumination. Also, sex organ weights, testicular and epididymal sperm count, sperm motility, daily sperm production, sperm transit rate and serum testosterone levels were measured. Lead acetate treatment resulted in a dose-response reduction of lengths of stages VIII and IX-XI, and serum testosterone levels. However, rats treated with 8 and 16mg/kg but not 24mg/kg of lead acetate showed a low number of testicular spermatids, low daily sperm production (DSP) and low epididymal sperm count. Administration of Maca to rats treated with lead acetate resulted in higher lengths of stages VIII and IX-XI with respect to lead acetate-treated rats. Moreover, treatment with Maca to lead acetate-treated rats resulted in lengths of stages VIII and IX-XI similar to the control group. Maca administration also reduced the deleterious effect on DSP caused by lead acetate treatment. Maca prevented LA-induced spermatogenic disruption in rats and it may become in a potential treatment of male infertility associated with lead exposure.

Effect of ethanol extract of Lepidium meyenii. on osteoporosis in ovariectomized rat.
J Ethnopharmacol. 2006.
School of Life Science & Technology, Huazhong University of Science & Technology, Wuhan, PR China.
Maca is a cruciferous plant from the Andes of Peru. The root of Maca is traditionally employed for its supposed properties in aphrodisiacs and improving fertility, it also has been widely used to help alleviate the symptoms of menopause. The purpose of this study was to evaluate the effect of ethanol extract of Maca on postmenopausal osteoporosis in ovariectomized rats. Female Sprague-Dawley rats were divided into four groups: Sham-operated and ovariectomized groups were fed with equivolume of distilled water, and the remaining ovariectomized groups were orally administrated with ethanol extract of Maca various doses for 28 weeks. The findings derived from the basis of bone mineral density, biomechanical, biochemical and histopathological parameters indicated that higher dose of ethanol extract of Maca was effective in the prevention of estrogen deficient bone loss.

Maca herb and wellbeing
Q. I’ve been taking maca powder every day and on some occasions every second day and feel an incredible difference in my wellbeing as a result of this. However, I have a cough which has come and gone over the past years and often persists for months at a time. I can not remember if I got the cough this time before I started talking maca or after but I have noticed that I start to develop more phlegm after taking maca herb which becomes extremely irritating. I know that phlegm it’s self is protein based and that maca has a high degree of absorbable protein and so I thought there may be some connection there. I only take half a tea spoon in hot water at a time when taking maca but I still feel the effects of plegm being produced after each time. I do not want to stop taking maca because I feel so great when I take it but at the same time this cough is driving me crazy. Do you think the way I am taking maca or the quantity that I’m taking is affiliated with this problem?
A. Even though phlegm is protein based, it would not have anything to do with protein in maca since people can eat chicken with protein and yet not have phlegm. We have not heard of maca causing phlegm or couth, but then again we don’t know many people who have taken maca for prolonged periods. It is always a good idea if a side effect is being suspected from an herb to take a break from it. There are many herbs that have overlapping functions and effects.

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How does Maca root work?
Maca root contains sterols, uridine, malic acid, macamides, and glucosinolates. Oil components include phenyl acetonitrile and benzaldehyde. Many of the compounds in maca have an effect on the central nervous system. The mechanism of action of maca is presently not well understood, but probably seems to be independent of a hormonal effect since studies show maca does not influence blood levels of hormones, for instance testosterone. Maca has alkaloids, steroids, tannins, saponins, and cardiotonic glycosides.

Maca supplement can be produced at NHK Laboratories in California